ATP7B polyclonal antibody
产品名称： ATP7B polyclonal antibody
英文名称： ATP7B polyclonal antibody
产品编号： PAB12477
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ATP7B.
- Immunogen:
- A synthetic peptide corresponding to N-terminus of human ATP7B.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Specificity:
- This antibody is specific to ATP7b.
- Form:
- Liquid
- Storage Buffer:
- In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Transport of cisplatin by the copper efflux transporter ATP7B.
Safaei R, Otani S, Larson BJ, Rasmussen ML, Howell SB.Mol Pharmacol. 2008 Feb;73(2):461-8. Epub 2007 Oct 31.
- Entrez GeneID:
- 540
- Protein Accession#:
- P35670
- Gene Name:
- ATP7B
- Gene Alias:
- PWD,WC1,WD,WND
- Gene Description:
- ATPase, Cu++ transporting, beta polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq
- Other Designations:
- ATPase, Cu(2+)- transporting, beta polypeptide,OTTHUMP00000040880,Wilson disease-associated protein,copper pump 2,copper-transporting ATPase 2